BIOLOGIE MOLECULAIRE SUR LE WEB

ANALYSES DE SEQUENCES	Comparaison de sequences Recherche de motifs Predictions de Structures secondaires Autres programmes...
BASES DE DONNEES	Interrogation de plusieurs banques, Banques de séquences, Banques génomiques Banques de motifs protéiques...
RECHERCHES BIBLIOGRAPHIQUES	Recherche dans Medline Journaux en ligne Archives...
AUTRES SERVEURS...

ANALYSES DE SEQUENCES

BLAST
[BLAST performs fast database searching combined with rigorous statistics for judging the significance of matches. Five BLAST programs search all combinations of query and database sequences. The BLAST algorithm is described in S.F. Altschul, W. Gish, W. Miller, E.W. Myers, and D.J. Lipman, J. Mol. Biol. 215, 403 (1990).]
FASTA
[FASTA is based on the FASTA program developed by Pearson and Lipman (1988, Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. U.S.A. 85:2444-2448) as implemented in the GCG package.
It allows you to perform fast and sensitive comparisons of your nucleic acid or protein sequences against various databases including the most recent EMBL entries.]
BLITZ
[BLITZ is an automatic electronic mail server for the MPsrch program of Shane Sturrock and John Collins, Biocomputing Research Unit, University of Edinburgh, Scotland.
MPsrch allows you to perform sensitive and extremely fast comparisons of your protein sequences against the Swiss-Prot protein sequence database using the Smith and Waterman best local similarity algorithm]
Sequence Alerting System
[The sequence alerting system in its present form will search each day in several databases for news on (homologues of) "your" sequence and will inform you by email if it has detected a new relative.]
PredictProtein
[An automatic service for the prediction of protein structure. You send an amino acid sequence and PredictProtein returns a multiple sequence alignment and predictions of secondary structure, residue solvent accessibility, and location of transmembrane helices. The following three features are available upon request: (1) fold recognition by prediction-based threading, PDB is searched for possible remote homologues (sequence identity 0-25%) to your sequence; (2) prediction of topology for helical transmembrane proteins; (3) evaluation of prediction accuracy, for a given predicted and observed secondary structure (for one or several proteins), per-residue and per-segment scores are compiled. For all services, you can submit your sequence (or prediction) either by electronic mail, or interactively from World Wide Web]
GenQuest
[An integrated interface to the sequence comparison server at the Oak Ridge National Lab designed for rapid and sensitive comparison of DNA and Protein sequence to existing DNA and Protein sequence databases and the rapid retrieval of the full database entries of any sequence found in the course of a search]
BCM Search Launcher
[The BCM Search Launcher is an on-going project to organize molecular biology-related search and analysis services available on the WWW by function by providing a single point-of-entry for related searches (e.g., a single page for launching protein sequence searches using standard parameters)]

BASES DE DONNEES

EMBL Nucleotide Sequence Database
[The EMBL Nucleotide Sequence Database is a comprehensive database of DNA and RNA sequences collected from the scientific literature and patent applications and directly submitted from researchers and sequencing groups. Data collection is done in collaboration with GenBank (USA) and the DNA Database of Japan (DDBJ)]
gdb
[The Genome Database (GDB) stores and curates genomic mapping data submitted by researchers worldwide and provides this information electronically to the scientific community]
Genbank
[GENBANK contains a large number of entries produced at the NLM, derived from scanning the biomedical literature]
dbEST
[dbEST (Nature Genetics 4:332-3;1993) is a division of GenBank that contains sequence data and other information on "single-pass" cDNA sequences, or Expressed Sequence Tags, from a number of organisms]
dbSTS
[dbSTS is a new NCBI resource that contains sequence and mapping data on short genomic landmark sequences or Sequence Tagged Sites]
Swissprot
[The SWISS-PROT Protein Sequence Database is a database of protein sequences produced collaboratively by Amos Bairoch (University of Geneva) and the EMBL Data Library. The data in Swiss-Prot are derived from translations of DNA sequences from the EMBL Nucleotide Sequence Database, adapted from the Protein Identification Resource (PIR) collection, extracted from the literature and directly submitted by researchers. It contains high-quality annotation,is non-redundant, and cross-referenced to several other databases, notably the EMBL nucleotide sequence database, PROSITE pattern database and PDB]
PROSITE
[The PROSITE dictionary of sites and patterns in proteins prepared by Amos Bairoch at the University of Geneva]
SCOP
[Structural Classification of Proteins]
The ProDom protein domain database
[The ProDom protein domain database consists of an automatic compilation of homologous domains detected in the SWISS-PROT database (Bairoch A, Boeckmann B, 1991, Nucleic Acids Res., 19:2247-2249) by the DOMAINER algorithm (Sonnhammer, E.L.L. & Kahn, D., 1994, Protein Sci. 3:482-492). It has been devised to assist with the analysis of the domain arrangement of proteins]
Entrez
[Entrez allows you to retrieve citations and records in the area of molecular biology from the NCBI databases. These include: The molecular biology subset of MEDLINE; Proteins from several databases around the world; Nucleotides from GenBank and other sources]
WebSub
[WebSub produces automatically-processable submissions. All submissions prepared with WebSub will be processed by GSDB and the results will be immediately forwarded on to the other databases (DDBJ, EMBL, and GenBank) for inclusion in their data collections]

RECHERCHES BIBLIOGRAPHIQUES

Entrez
[Search the molecular biology subset of MEDLINE]
The World-Wide Web Virtual Library: Biosciences
Biosci
BIOSCI is a set of electronic communication forums - the bionet USENET newsgroups and parallel e-mail lists - used by biological scientists worldwide.
- Bionet newsgroup
  WWW Interface to the BIOSCI/bionet newsgroups; includes a complete archive and searchable indexes of all BIOSCI/bionet newsgroup postings.
- Bionet.journals.content
  Browse the tables of contents of all of the journals distributed on the BIO-JOURNALS/bionet.journals.contents newsgroup or search for references on the topic of your choice.
- user address database
  Search the BIOSCI user address database by name, address, research interest, etc. All terms in each user entry are indexed.
MedWeb: Electronic Newsletters and Journals

AUTRES SERVEURS...

EMBL (European Molecular Biology Laboratory)
EBI (European Bioinformatics Institute)
ExPASy Molecular Biology server
NCBI
Généthon
Listes de serveurs maintenues par INFOBIOGEN (Villejuif)

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